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GATA-6 Polyclonal Antibody, 100μg, (ATB-T1865)

$199.00
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Product Details

Background: This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012]Product datasheet: Overview Product Description GATA-6 Polyclonal Antibody, 100μg, (ATB-T1865) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human GATA-6. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Two functional sequence variants of the GATA6 gene promoter in patients with indirect inguinal hernia. Qiao Y, et al. Gene, 2014 Aug 15. PMID 24949533 Identification of two novel GATA6 mutations in patients with nonsyndromic conotruncal heart defects. Wang X, et al. Mol Med Rep, 2014 Aug. PMID 24841381 Whole exome sequencing identifies de novo mutations in GATA6 associated with congenital diaphragmatic hernia. Yu L, et al. J Med Genet, 2014 Mar. PMID 24385578 Free PMC Article An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer. Sulahian R, et al. Oncogene, 2014 Dec 4. PMID 24317510 A case of pancreatic agenesis and congenital heart defects with a novel GATA6 nonsense mutation: evidence of haploinsufficiency due to nonsense-mediated mRNA decay. Suzuki S, et al. Am J Med Genet A, 2014 Feb. PMID 24310933

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GATA-6 Polyclonal Antibody, 100μg, (ATB-T1865)
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