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GDI-2 Polyclonal Antibody, 100μg, (ATB-T15317)

$199.00
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Background: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description GDI-2 Polyclonal Antibody, 100μg, (ATB-T15317) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human GDI-2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Pericentriolar targeting of GDP-dissociation inhibitor isoform 2. Shisheva A, et al. Eur J Cell Biol, 1995 Oct. PMID 8575461 Differential intracellular localizations of GDP dissociation inhibitor isoforms. Insulin-dependent redistribution of GDP dissociation inhibitor-2 in 3T3-L1 adipocytes. Shisheva A, et al. J Biol Chem, 1994 Sep 30. PMID 7929030 Serum proteomic-based analysis of pancreatic carcinoma for the identification of potential cancer biomarkers. Sun ZL, et al. Biochim Biophys Acta, 2007 Jun. PMID 17507299 Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain. Weitzdoerfer R, et al. J Neural Transm Suppl, 2001. PMID 11771757 The human rab GDI beta gene with long retroposon-rich introns maps to 10p15 and its pseudogene to 7p11-p13. Sedlacek Z, et al. Mamm Genome, 1998 Jan. PMID 9434952

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GDI-2 Polyclonal Antibody, 100μg, (ATB-T15317)
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