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GPR91 Polyclonal Antibody, 100μg, (ATB-T2035)

$199.00
In stock
Product Details

Background: This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009]Product datasheet: Overview Product Description GPR91 Polyclonal Antibody, 100μg, (ATB-T2035) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human GPR91. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Succinate receptor GPR91, a Gα(i) coupled receptor that increases intracellular calcium concentrations through PLCβ. Sundström L, et al. FEBS Lett, 2013 Aug 2. PMID 23770096 The role of the GPR91 ligand succinate in hematopoiesis. Hakak Y, et al. J Leukoc Biol, 2009 May. PMID 19204147 Deficiency in the metabolite receptor SUCNR1 (GPR91) leads to outer retinal lesions. Favret S, et al. Aging (Albany NY), 2013 Jun. PMID 23833031 Free PMC Article Neovascularization in retinopathy of prematurity: opposing actions of neuronal factors GPR91 and semaphorins 3A. Joyal JS, et al. Acta Paediatr, 2012 Aug. PMID 22497252 Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. He W, et al. Nature, 2004 May 13. PMID 15141213

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GPR91 Polyclonal Antibody, 100μg, (ATB-T2035)
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