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Gab 2 Polyclonal Antibody, 100μg, (ATB-T1817)
Background: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]Product datasheet: Overview Product Description Gab 2 Polyclonal Antibody, 100μg, (ATB-T1817) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Gab 2 around the non-phosphorylation site of Y643. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene. Dunn GP, et al. Proc Natl Acad Sci U S A, 2014 Jan 21. PMID 24385586 Free PMC Article Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model. Zhan A, et al. Synapse, 2014 Apr. PMID 24327320 GAB2 polymorphism rs2373115 confers susceptibility to sporadic Alzheimer's disease. Jin C, et al. Neurosci Lett, 2013 Nov 27. PMID 24161894 Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology. Zou F, et al. PLoS One, 2013. PMID 23724096 Free PMC Article Gab2 expression in glioma and its implications for tumor invasion. Shi L, et al. Acta Oncol, 2013 Nov. PMID 23231021
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Why is IntelixBio LLC so popular?
IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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How can I contact your company?
You can reach IntelixBio LLC by phone at 240-316-3161, by email at info@intelixbio.com, or by filling out one of the contact forms on our website.
When you contact our team, you can expect fast, friendly, and professional assistance with all your medical lab equipment needs.