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Ghrelin Polyclonal Antibody, 100μg, (ATB-T1900)
Background: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]Product datasheet: Overview Product Description Ghrelin Polyclonal Antibody, 100μg, (ATB-T1900) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Ghrelin. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Evaluation of ghrelin level and appetite regulation in patients with acute exacerbations of chronic obstructive pulmonary disease. Wang Y, et al. Int J Chron Obstruct Pulmon Dis, 2014. PMID 25152618 Free PMC Article Immunohistochemical evidence of association between ghrelin expression and tumor growth in esophageal carcinoma. Omoto I, et al. Anticancer Res, 2014 Jun. PMID 24922633 [Effect of ghrelin on colonic motility]. Hirayama H, et al. Nihon Yakurigaku Zasshi, 2014 Jun. PMID 24919551 Plasma ghrelin concentrations are negatively correlated with urine albumin-to-creatinine ratio in newly diagnosed type 2 diabetes. Ma X, et al. Am J Med Sci, 2014 Nov. PMID 24875659 Association between ghrelin gene variations, body mass index, and waist-to-hip ratio in patients with polycystic ovary syndrome. Xu L, et al. Exp Clin Endocrinol Diabetes, 2014 Mar. PMID 24643690
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At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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- Protective gear
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