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Gα 14 Polyclonal Antibody, 100μg, (ATB-T2091)

$199.00
In stock
Product Details

Background: This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]Product datasheet: Overview Product Description Gα 14 Polyclonal Antibody, 100μg, (ATB-T2091) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the N-terminal region of human Gα 14. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The importance of N-terminal polycysteine and polybasic sequences for G14alpha and G16alpha palmitoylation, plasma membrane localization, and signaling function. Pedone KH, et al. J Biol Chem, 2007 Aug 31. PMID 17620339 Interaction with Gbetagamma is required for membrane targeting and palmitoylation of Galpha(s) and Galpha(q). Evanko DS, et al. J Biol Chem, 2000 Jan 14. PMID 10625681 Genomic organization of the human galpha14 and Galphaq genes and mutation analysis in chorea-acanthocytosis (CHAC). Rubio JP, et al. Genomics, 1999 Apr 1. PMID 10191087 Activation of Ras-dependent signaling pathways by G(14) -coupled receptors requires the adaptor protein TPR1. Kwan DH, et al. J Cell Biochem, 2012 Nov. PMID 22711498 Selective G protein coupling by C-C chemokine receptors. Kuang Y, et al. J Biol Chem, 1996 Feb 23. PMID 8626727

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Gα 14 Polyclonal Antibody, 100μg, (ATB-T2091)
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