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HDAC7 Polyclonal Antibody, 100μg, (ATB-T2119)
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description HDAC7 Polyclonal Antibody, 100μg, (ATB-T2119) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human HDAC7 around the non-phosphorylation site of S155. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages. Barneda-Zahonero B, et al. PLoS Genet, 2013 May. PMID 23696748 Free PMC Article The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc. Zhu C, et al. J Mol Med (Berl), 2011 Mar. PMID 21120446 [RNA interference of HDAC7 expression in hepatocellular carcinoma]. Zhang G, et al. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2010 Jul. PMID 20693714 High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Ouaïssi M, et al. Ann Surg Oncol, 2008 Aug. PMID 18506539 Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. Schuetz A, et al. J Biol Chem, 2008 Apr 25. PMID 18285338 Free PMC Article
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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