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HSC 70 Polyclonal Antibody, 100μg, (ATB-T2232)

$199.00
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Background: This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]Product datasheet: Overview Product Description HSC 70 Polyclonal Antibody, 100μg, (ATB-T2232) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human HSC 70. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: HSP70 polymorphisms in first psychotic episode drug-naïve schizophrenic patients. Bozidis P, et al. Life Sci, 2014 Apr 1. PMID 24548631 Reduced expression of the chaperone-mediated autophagy carrier hsc70 protein in lymphomonocytes of patients with Parkinson's disease. Sala G, et al. Brain Res, 2014 Feb 10. PMID 24361989 The cellular chaperone hsc70 is specifically recruited to reovirus viral factories independently of its chaperone function. Kaufer S, et al. J Virol, 2012 Jan. PMID 22090113 Free PMC Article Generation of a rat monoclonal antibody specific for heat shock cognate protein 70. Shiota M, et al. Hybridoma (Larchmt), 2010 Oct. PMID 21050049 Arginine 469 is a pivotal residue for the Hsc70-GlcNAc-binding property. Guinez C, et al. Biochem Biophys Res Commun, 2010 Oct 1. PMID 20804732

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HSC 70 Polyclonal Antibody, 100μg, (ATB-T2232)
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