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Hic-5 Polyclonal Antibody, 100μg, (ATB-T2132)

$199.00
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Background: This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]Product datasheet: Overview Product Description Hic-5 Polyclonal Antibody, 100μg, (ATB-T2132) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Hic-5 around the non-phosphorylation site of Y60. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Multipotential functions of Hic-5 in growth, differentiation, migration and adhesion of human keratinocytes. Inui S, et al. J Dermatol Sci, 2012 Dec. PMID 23062781 [Hydrogen peroxide-inducible clone 5 (Hic-5) as a potential therapeutic target]. Kim-Kaneyama JR. Seikagaku, 2012 Apr. PMID 22712231 Glomerular expression of hydrogen peroxide-inducible clone-5 in human and rat progressive mesangial proliferative glomerulonephritis. Suga K, et al. Nephron Exp Nephrol, 2012. PMID 22286178 Paxillin and hydrogen peroxide-inducible clone 5 expression and distribution in control and Alzheimer disease hippocampi. Caltagarone J, et al. J Neuropathol Exp Neurol, 2010 Apr. PMID 20448481 Free PMC Article In vitro and in vivo evidence of pathogenic roles of Hic-5/ARA55 in keloids through Smad pathway and profibrotic transcription. Inui S, et al. J Dermatol Sci, 2010 May. PMID 20395114

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Hic-5 Polyclonal Antibody, 100μg, (ATB-T2132)
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