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Histone H4 Polyclonal Antibody, 100μg, (ATB-T2174)

$199.00
In stock
Product Details

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Histone H4 Polyclonal Antibody, 100μg, (ATB-T2174) Image Species Reactivities Human,Mouse,Rat,Monkey Immunogen Synthesized peptide derived from human Histone H4 around the non-acetylation site of K8. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Acetylation changes at lysine 5 of histone H4 associated with lytic gene promoters during reactivation of Kaposi's sarcoma-associated herpesvirus. Hwang LR, et al. Acta Virol, 2014. PMID 25283865 Global proteome quantification for discovering imatinib-induced perturbation of multiple biological pathways in K562 human chronic myeloid leukemia cells. Xiong L, et al. J Proteome Res, 2010 Nov 5. PMID 20949922 Free PMC Article PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression. Congdon LM, et al. J Cell Biochem, 2010 Jun 1. PMID 20512922 Real-time imaging of histone H4 hyperacetylation in living cells. Sasaki K, et al. Proc Natl Acad Sci U S A, 2009 Sep 22. PMID 19805290 Free PMC Article Histone H4 is a major component of the antimicrobial action of human sebocytes. Lee DY, et al. J Invest Dermatol, 2009 Oct. PMID 19536143 Free PMC Article

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Histone H4 Polyclonal Antibody, 100μg, (ATB-T2174)
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