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HoxD10 Polyclonal Antibody, 100μg, (ATB-T2219)
Background: This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description HoxD10 Polyclonal Antibody, 100μg, (ATB-T2219) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the C-terminal region of human HoxD10. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC). Hakami F, et al. Br J Cancer, 2014 Aug 12. PMID 25010866 Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis. Wang L, et al. Mol Med, 2012 May 9. PMID 22160393 Free PMC Article Absence of HOXD10 mutations in idiopathic clubfoot and sporadic vertical talus. Gurnett CA, et al. Clin Orthop Relat Res, 2007 Sep. PMID 17417092 Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model. Carrio M, et al. Cancer Res, 2005 Aug 15. PMID 16103068 Congenital vertical talus in four generations of the same family. Levinsohn EM, et al. Skeletal Radiol, 2004 Nov. PMID 15368082
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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