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IF3 Polyclonal Antibody, 100μg, (ATB-T2273)

$199.00
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Background: This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009]Product datasheet: Overview Product Description IF3 Polyclonal Antibody, 100μg, (ATB-T2273) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human IF3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Possible involvement of a mitochondrial translation initiation factor 3 variant causing decreased mRNA levels in Parkinson's disease. Anvret A, et al. Parkinsons Dis, 2010 Jun 14. PMID 20976088 Free PMC Article Mitochondrial translation initiation factor 3 polymorphism and Parkinson's disease. Behrouz B, et al. Neurosci Lett, 2010 Dec 17. PMID 20887776 Evidence for an active role of IF3mt in the initiation of translation in mammalian mitochondria. Christian BE, et al. Biochemistry, 2009 Apr 21. PMID 19239245 Free PMC Article The interaction of mammalian mitochondrial translational initiation factor 3 with ribosomes: evolution of terminal extensions in IF3mt. Haque ME, et al. Nucleic Acids Res, 2008 Feb. PMID 18056078 Free PMC Article Overexpression and purification of mammalian mitochondrial translational initiation factor 2 and initiation factor 3. Grasso DG, et al. Methods Enzymol, 2007. PMID 17913635

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IF3 Polyclonal Antibody, 100μg, (ATB-T2273)
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