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IGF2-BP2 Polyclonal Antibody, 100μg, (ATB-T2284)

$199.00
In stock
Product Details

Background: This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms. [provided by RefSeq, May 2014]Product datasheet: Overview Product Description IGF2-BP2 Polyclonal Antibody, 100μg, (ATB-T2284) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human IGF2-BP2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: VICKZ2 protein expression in ovarian serous carcinoma effusions is associated with poor survival. Davidson B, et al. Hum Pathol, 2014 Jul. PMID 24814803 Replication of association study between type 2 diabetes mellitus and IGF2BP2 in Han Chinese population. Zhang SM, et al. Chin Med J (Engl), 2013 Nov. PMID 24229666 The type 2 diabetes mellitus susceptibility gene IGF2BP2 is associated with schizophrenia in a Han Chinese population. Zhang X, et al. J Clin Psychiatry, 2013 Apr. PMID 23656854 Humoral autoimmune response to IGF2 mRNA-binding protein (IMP2/p62) and its tissue-specific expression in colon cancer. Liu W, et al. Scand J Immunol, 2013 Apr. PMID 23421499 The rs11705701 G>A polymorphism of IGF2BP2 is associated with IGF2BP2 mRNA and protein levels in the visceral adipose tissue - a link to type 2 diabetes susceptibility. Chistiakov DA, et al. Rev Diabet Stud, 2012 Summer-Fall. PMID 23403707 Free PMC Article

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IGF2-BP2 Polyclonal Antibody, 100μg, (ATB-T2284)
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