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IK Polyclonal Antibody, 100μg, (ATB-T2297)

$199.00
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Product Details

Background: The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description IK Polyclonal Antibody, 100μg, (ATB-T2297) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human IK. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The interferon inhibiting cytokine IK is overexpressed in cutaneous T cell lymphoma derived tumor cells that fail to upregulate major histocompatibility complex class II upon interferon-gamma stimulation. Willers J, et al. J Invest Dermatol, 2001 Jun. PMID 11407974 Implication of a new molecule IK in CD34+ hematopoietic progenitor cell proliferation and differentiation. Cao LX, et al. Blood, 1997 May 15. PMID 9160666 RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint. Yeh PC, et al. J Biol Chem, 2012 Apr 6. PMID 22351768 Free PMC Article Isolation, sequencing and expression of RED, a novel human gene encoding an acidic-basic dipeptide repeat. Assier E, et al. Gene, 1999 Apr 16. PMID 10216252 A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization. Krief P, et al. Oncogene, 1994 Dec. PMID 7970704

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IK Polyclonal Antibody, 100μg, (ATB-T2297)
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