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IL-13Rα2 Polyclonal Antibody, 100μg, (ATB-T2314)

$199.00
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Product Details

Background: The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description IL-13Rα2 Polyclonal Antibody, 100μg, (ATB-T2314) Image Species Reactivities Human Immunogen Synthesized peptide derived from the C-terminal region of human IL-13Rα2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Glioma IL13Rα2 is associated with mesenchymal signature gene expression and poor patient prognosis. Brown CE, et al. PLoS One, 2013. PMID 24204956 Free PMC Article High expression of IL-13 receptor α2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis. Barderas R, et al. Cancer Res, 2012 Jun 1. PMID 22505647 IL-13 regulates cancer invasion and metastasis through IL-13Rα2 via ERK/AP-1 pathway in mouse model of human ovarian cancer. Fujisawa T, et al. Int J Cancer, 2012 Jul 15. PMID 21858811 IL-13 antibodies influence IL-13 clearance in humans by modulating scavenger activity of IL-13Rα2. Kasaian MT, et al. J Immunol, 2011 Jul 1. PMID 21622864 Silencing IL-13Rα2 promotes glioblastoma cell death via endogenous signaling. Hsi LC, et al. Mol Cancer Ther, 2011 Jul. PMID 21596889 Free PMC Article

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IL-13Rα2 Polyclonal Antibody, 100μg, (ATB-T2314)
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