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IL-2Rβ Polyclonal Antibody, 100μg, (ATB-T2330)

$199.00
In stock
Product Details

Background: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description IL-2Rβ Polyclonal Antibody, 100μg, (ATB-T2330) Image Species Reactivities Human,Mouse,Rat,Monkey Immunogen Synthesized peptide derived from human IL-2Rβ around the non-phosphorylation site of Y364. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Abnormal expression pattern of the IL-2 receptor β-chain on CD4+ T cells in ANCA-associated vasculitis. Wilde B, et al. Dis Markers, 2014. PMID 24648606 Free PMC Article Oxalate upregulates expression of IL-2Rβ and activates IL-2R signaling in HK-2 cells, a line of human renal epithelial cells. Koul S, et al. Am J Physiol Renal Physiol, 2014 May 1. PMID 24523387 Neutrality of miniSTR D22S1045 marker by Ewing's sarcoma phenotype. Silva DS, et al. Leg Med (Tokyo), 2013 Nov. PMID 24112992 Placenta-specific expression of the interleukin-2 (IL-2) receptor β subunit from an endogenous retroviral promoter. Cohen CJ, et al. J Biol Chem, 2011 Oct 14. PMID 21865161 Free PMC Article Ectodomain shedding of interleukin-2 receptor beta and generation of an intracellular functional fragment. Montes de Oca P, et al. J Biol Chem, 2010 Jul 16. PMID 20495002 Free PMC Article

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IL-2Rβ Polyclonal Antibody, 100μg, (ATB-T2330)
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