IL-5 Polyclonal Antibody, 100µg, (ATB-T2339)

Background: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.Product datasheet: Overview Product Description IL-5 Polyclonal Antibody, 100µg, (ATB-T2339) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human IL-5. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year Clonality Polyclonal References: Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue. Azuma C., Tanabe T., Konishi M., Kinashi T., Noma T., Matsuda F., Yaoita Y., Takatsu K., Hammarstroem L., Smith C.I.E., Severinson E., Honjo T.Nucleic Acids Res. 14:9149-9158(1986) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Molecular cloning and structure of the human interleukin-5 gene. Tanabe T., Konishi M., Mizuta T., Noma T., Honjo T.J. Biol. Chem. 262:16580-16584(1987) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5). Campbell H.D., Tucker W.Q.J., Hort Y., Martinson M.E., Mayo G., Clutterbuck E.J., Sanderson C.J., Young I.G.Proc. Natl. Acad. Sci. U.S.A. 84:6629-6633(1987) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5. Yokota T., Coffman R.L., Hagiwara H., Rennick D.M., Takebe Y., Yokota K., Gemmell L., Shrader B., Yang G., Meyerson P., Luh J., Hoy P., Pene J., Briere F., Spits H., Banchereau J., de Vries J., Lee F.D., Arai N., Arai K.Proc. Natl. Acad. Sci. U.S.A. 84:7388-7392(1987) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Honjo T., Takatsu K., Severinson E.Submitted (FEB-1992) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. SeattleSNPs variation discovery resourceSubmitted (FEB-2001) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Structure of recombinant human interleukin 5 produced by Chinese hamster ovary cells. Minamitake Y., Kodama S., Katayama T., Adachi H., Tanaka S., Tsujimoto M.J. Biochem. 107:292-297(1990) [PubMed] [Europe PMC] Cited for: PROTEIN SEQUENCE OF 20-134, DISULFIDE BONDS, GLYCOSYLATION AT THR-22 AND ASN-47, LACK OF GLYCOSYLATION AT ASN-90. Human interleukin-5 expressed in Escherichia coli: assignment of the disulfide bridges of the purified unglycosylated protein. Proudfoot A.E.I., Davies J.G., Turcatti G., Wingfield P.T.FEBS Lett. 283:61-64(1991) [PubMed] [Europe PMC] Cited for: DISULFIDE BONDS. A novel dimer configuration revealed by the crystal structure at 2.4-A resolution of human interleukin-5. Milburn M.V., Hassell A.M., Lambert M.H., Jordan S.R., Proudfoot A.E.I., Graber P., Wells T.N.C.Nature 363:172-176(1993) [PubMed] [Europe PMC] Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS), DISULFIDE BONDS.