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IP Receptor Polyclonal Antibody, 100μg, (ATB-T2378)

$199.00
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Product Details

Background: The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description IP Receptor Polyclonal Antibody, 100μg, (ATB-T2378) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human IP Receptor. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function. Bill A, et al. PLoS One, 2014. PMID 24886841 Free PMC Article Prostaglandin I2-IP signalling regulates human Th17 and Treg cell differentiation. Liu W, et al. Prostaglandins Leukot Essent Fatty Acids, 2013 Oct. PMID 24035274 Effect of single nucleotide polymorphisms of the prostacyclin receptor gene on platelet activation in Japanese healthy subjects and patients with cerebral infarction. Shimizu M, et al. J Clin Neurosci, 2013 Jun. PMID 23628440 Regulation of the human prostacyclin receptor gene in megakaryocytes: major roles for C/EBPδ and PU.1. Keating GL, et al. Biochim Biophys Acta, 2012 May. PMID 22381139 Comprehensive biochemical analysis of rare prostacyclin receptor variants: study of association of signaling with coronary artery obstruction. Stitham J, et al. J Biol Chem, 2011 Mar 4. PMID 21189259 Free PMC Article

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IP Receptor Polyclonal Antibody, 100μg, (ATB-T2378)
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