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IRE1α/β Polyclonal Antibody, 100μg, (ATB-T2394)

$199.00
In stock
Product Details

Background: Product datasheet: Overview Product Description IRE1α/β Polyclonal Antibody, 100μg, (ATB-T2394) Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the C-terminal region of human IRE1α/β. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Direct association of unfolded proteins with mammalian ER stress sensor, IRE1β. Oikawa D, et al. PLoS One, 2012. PMID 23236464 Free PMC Article Mammalian ER stress sensor IRE1β specifically down-regulates the synthesis of secretory pathway proteins. Nakamura D, et al. FEBS Lett, 2011 Jan 3. PMID 21146530 The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Zhou J, et al. Proc Natl Acad Sci U S A, 2006 Sep 26. PMID 16973740 Free PMC Article A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response. Niwa M, et al. Cell, 1999 Dec 23. PMID 10619423 RNase domains determine the functional difference between IRE1alpha and IRE1beta. Imagawa Y, et al. FEBS Lett, 2008 Mar 5. PMID 18242182

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IRE1α/β Polyclonal Antibody, 100μg, (ATB-T2394)
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