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Internexin-α Polyclonal Antibody, 100μg, (ATB-T2374)

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Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons. [provided by RefSeq, Jun 2009]Product datasheet: Overview Product Description Internexin-α Polyclonal Antibody, 100μg, (ATB-T2374) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Internexin-α. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: α-Internexin: a novel biomarker for pancreatic neuroendocrine tumor aggressiveness. Liu B, et al. J Clin Endocrinol Metab, 2014 May. PMID 24483152 The clinical implications and biologic relevance of neurofilament expression in gastroenteropancreatic neuroendocrine neoplasms. Schimmack S, et al. Cancer, 2012 May 15. PMID 21990041 Free PMC Article alpha-Internexin expression identifies 1p19q codeleted gliomas. Ducray F, et al. Neurology, 2009 Jan 13. PMID 19139367 Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease. Armstrong RA, et al. Eur J Neurol, 2006 May. PMID 16722980 alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease. Cairns NJ, et al. Am J Pathol, 2004 Jun. PMID 15161649 Free PMC Article

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Internexin-α Polyclonal Antibody, 100μg, (ATB-T2374)