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KV2.1 Polyclonal Antibody, 100μg, (ATB-T2509)

$199.00
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Product Details

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description KV2.1 Polyclonal Antibody, 100μg, (ATB-T2509) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human KV2.1 around the non-phosphorylation site of S805. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: De novo KCNB1 mutations in epileptic encephalopathy. Torkamani A, et al. Ann Neurol, 2014 Oct. PMID 25164438 An exploratory study of the association between KCNB1 rs1051295 and type 2 diabetes and its related traits in Chinese Han population. Zhang YX, et al. PLoS One, 2013. PMID 23431371 Free PMC Article Toxic role of K+ channel oxidation in mammalian brain. Cotella D, et al. J Neurosci, 2012 Mar 21. PMID 22442077 Dynamic modulation of the kv2.1 channel by SRC-dependent tyrosine phosphorylation. Song MY, et al. J Proteome Res, 2012 Feb 3. PMID 22106938 Free PMC Article Functional interactions between residues in the S1, S4, and S5 domains of Kv2.1. Bocksteins E, et al. Eur Biophys J, 2011 Jun. PMID 21455829

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KV2.1 Polyclonal Antibody, 100μg, (ATB-T2509)
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