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Ku-70 Polyclonal Antibody, 100μg, (ATB-T2498)
Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Ku-70 Polyclonal Antibody, 100μg, (ATB-T2498) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human Ku-70. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Association of X-ray repair cross-complementing-6 genotypes with childhood leukemia. Pei JS, et al. Anticancer Res, 2013 Dec. PMID 24324074 Association between the XRCC6 Promoter rs2267437 polymorphism and cancer risk: evidence based on the current literature. Xu H, et al. Genet Test Mol Biomarkers, 2013 Aug. PMID 23745766 Free PMC Article Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer. Alshareeda AT, et al. Breast Cancer Res Treat, 2013 Jun. PMID 23624778 The contribution of XRCC6/Ku70 to hepatocellular carcinoma in Taiwan. Hsu CM, et al. Anticancer Res, 2013 Feb. PMID 23393345 Castration therapy results in decreased Ku70 levels in prostate cancer. Al-Ubaidi FL, et al. Clin Cancer Res, 2013 Mar 15. PMID 23349316
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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