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LRP1 Polyclonal Antibody, 100μg, (ATB-T2589)

$199.00
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Background: The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010]Product datasheet: Overview Product Description LRP1 Polyclonal Antibody, 100μg, (ATB-T2589) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from human LRP1 around the non-phosphorylation site of S4520. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Regulation of LRP-1 expression: make the point. Emonard H, et al. Pathol Biol (Paris), 2014 Apr. PMID 24661974 Properties of human blood monocytes. I. CD91 expression and log orthogonal light scatter provide a robust method to identify monocytes that is more accurate than CD14 expression. Hudig D, et al. Cytometry B Clin Cytom, 2014 Mar. PMID 24591168 Molecular and functional characterization of LRP1 promoter polymorphism c.1-25 C>G (rs138854007). Aledo R, et al. Atherosclerosis, 2014 Mar. PMID 24529141 The hypolipidemic effect of cilostazol can be mediated by regulation of hepatic low-density lipoprotein receptor-related protein 1 (LRP1) expression. Kim HJ, et al. Metabolism, 2014 Jan. PMID 24139096 A pilot study on low-density lipoprotein receptor-related protein-1 in Chinese patients with abdominal aortic aneurysm. Chan CY, et al. Eur J Vasc Endovasc Surg, 2013 Nov. PMID 24054777

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LRP1 Polyclonal Antibody, 100μg, (ATB-T2589)
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