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Lipocalin-1 Polyclonal Antibody, 100μg, (ATB-T15219)

$199.00
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Background: This gene encodes a member of the lipocalin family of small secretory proteins. Lipocalins are extracellular transport proteins that bind to a variety of hydrophobic ligands. The encoded protein is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. The encoded protein may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and two pseudogenes of this gene are also located on the long arm of chromosome 9. [provided by RefSeq, Nov 2011]Product datasheet: Overview Product Description Lipocalin-1 Polyclonal Antibody, 100μg, (ATB-T15219) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human Lipocalin-1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The conserved disulfide bond of human tear lipocalin modulates conformation and lipid binding in a ligand selective manner. Gasymov OK, et al. Biochim Biophys Acta, 2011 May. PMID 21466861 Free PMC Article Lipocalin-1: a potential marker for noninvasive aneuploidy screening. McReynolds S, et al. Fertil Steril, 2011 Jun 30. PMID 21324447 A new crystal form of human tear lipocalin reveals high flexibility in the loop region and induced fit in the ligand cavity. Breustedt DA, et al. Acta Crystallogr D Biol Crystallogr, 2009 Oct. PMID 19770509 Free PMC Article Intracavitary ligand distribution in tear lipocalin by site-directed tryptophan fluorescence. Gasymov OK, et al. Biochemistry, 2009 Aug 4. PMID 19586017 Tear lipocalin is the major endonuclease in tears. Yusifov TN, et al. Mol Vis, 2008 Jan 29. PMID 18334931 Free PMC Article

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Lipocalin-1 Polyclonal Antibody, 100μg, (ATB-T15219)
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