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MIP-1β Polyclonal Antibody, 100μg, (ATB-T15207)

$199.00
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Product Details

Background: This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]Product datasheet: Overview Product Description MIP-1β Polyclonal Antibody, 100μg, (ATB-T15207) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human MIP-1β. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Functional redundancy of the human CCL4 and CCL4L1 chemokine genes. Howard OM, et al. Biochem Biophys Res Commun, 2004 Jul 30. PMID 15240137 Comparison of a quantitative Real-Time PCR assay and droplet digital PCR for copy number analysis of the CCL4L genes. Bharuthram A, et al. Infect Genet Evol, 2014 Jul. PMID 24727646 CCL4L polymorphisms and CCL4/CCL4L serum levels are associated with psoriasis severity. Pedrosa E, et al. J Invest Dermatol, 2011 Sep. PMID 21614014 Cloning and expression of a lymphocyte activation gene (LAG-1). Baixeras E, et al. Mol Immunol, 1990 Nov. PMID 2247088 Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients. Colobran R, et al. J Immunol, 2005 May 1. PMID 15843566

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MIP-1β Polyclonal Antibody, 100μg, (ATB-T15207)
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