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MSK2 Polyclonal Antibody, 100μg, (ATB-T2903)

$199.00
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Product Details

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description MSK2 Polyclonal Antibody, 100μg, (ATB-T2903) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from human MSK2 around the non-phosphorylation site of T568. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: A transcript map of an 800-kb region on human chromosome 11q13, part of the candidate region for SCA5 and BBS1. Zhu S, et al. Hum Genet, 1998 Dec. PMID 9921902 HCV-induced PKR activation is stimulated by the mitogen- and stress-activated protein kinase MSK2. Kang JI, et al. Biochem Biophys Res Commun, 2011 Apr 1. PMID 21385567 MSK activation and physiological roles. Arthur JS. Front Biosci, 2008 May 1. PMID 18508628 C-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB). Tomás-Zuber M, et al. J Biol Chem, 2001 Feb 23. PMID 11035004 Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction. Khan P, et al. PLoS One, 2013. PMID 23675462 Free PMC Article

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MSK2 Polyclonal Antibody, 100μg, (ATB-T2903)
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