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Med8 Polyclonal Antibody, 100μg, (ATB-T2697)

$199.00
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Product Details

Background: This gene encodes a protein component of the mediator complex, which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function in ubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]Product datasheet: Overview Product Description Med8 Polyclonal Antibody, 100μg, (ATB-T2697) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Med8. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability. Williams DS, et al. PLoS One, 2010 Dec 31. PMID 21209843 Free PMC Article Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response. Léonard VH, et al. J Virol, 2006 Oct. PMID 16973571 Free PMC Article The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism. van Knippenberg I, et al. J Gen Virol, 2010 Aug. PMID 20427562 Free PMC Article Screening and identification of host factors interacting with UL14 of herpes simplex virus 1. Wu F, et al. Med Microbiol Immunol, 2011 Aug. PMID 21512757 MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor gamma and is required for full transcriptional activity and adipogenesis. Grøntved L, et al. Mol Cell Biol, 2010 May. PMID 20194623 Free PMC Article

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Med8 Polyclonal Antibody, 100μg, (ATB-T2697)
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