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Msx-2 Polyclonal Antibody, 100μg, (ATB-T2905)

$199.00
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Product Details

Background: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Msx-2 Polyclonal Antibody, 100μg, (ATB-T2905) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the Internal region of human Msx-2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Boston type craniosynostosis: report of a second mutation in MSX2. Florisson JM, et al. Am J Med Genet A, 2013 Oct. PMID 23949913 Microduplications upstream of MSX2 are associated with a phenocopy of cleidocranial dysplasia. Ott CE, et al. J Med Genet, 2012 Jul. PMID 22717651 Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma. Gremel G, et al. Br J Cancer, 2011 Aug 9. PMID 21730974 Free PMC Article MSX2 is an oncogenic downstream target of activated WNT signaling in ovarian endometrioid adenocarcinoma. Zhai Y, et al. Oncogene, 2011 Oct 6. PMID 21499300 Free PMC Article The evaluation of MSX2 mRNA expression level in biliary brush cytological specimens. Ito H, et al. Anticancer Res, 2011 Mar. PMID 21498730

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Msx-2 Polyclonal Antibody, 100μg, (ATB-T2905)
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