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NF-M Polyclonal Antibody, 100μg, (ATB-T3088)

$199.00
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Product Details

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]Product datasheet: Overview Product Description NF-M Polyclonal Antibody, 100μg, (ATB-T3088) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human NF-M. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Association of the dopamine receptor interacting protein gene, NEF3, with early response to antipsychotic medication. Strous RD, et al. Int J Neuropsychopharmacol, 2007 Jun. PMID 16734940 The G336S variant in the human neurofilament-M gene does not affect its assembly or distribution: importance of the functional analysis of neurofilament variants. Perez-Olle R, et al. J Neuropathol Exp Neurol, 2004 Jul. PMID 15290901 Mutation analysis of the neurofilament M gene in Parkinson's disease. Krüger R, et al. Neurosci Lett, 2003 Nov 13. PMID 14583397 Transcription of intermediate filament genes is enhanced in focal cortical dysplasia. Taylor JP, et al. Acta Neuropathol, 2001 Aug. PMID 11563628 The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. Myers MW, et al. EMBO J, 1987 Jun. PMID 3608989 Free PMC Article

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NF-M Polyclonal Antibody, 100μg, (ATB-T3088)
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