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NMBR Polyclonal Antibody, 100μg, (ATB-T3148)

$199.00
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Background: Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description NMBR Polyclonal Antibody, 100μg, (ATB-T3148) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human NMBR. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor. Sainz E, et al. J Biol Chem, 1998 Jun 26. PMID 9632639 Differential activation of human gastrin-releasing peptide receptor-mediated responses by bombesin analogs. Wu JM, et al. Mol Pharmacol, 1995 Apr. PMID 7723750 Hypoxia regulates the expression of the neuromedin B receptor through a mechanism dependent on hypoxia-inducible factor-1α. Park HJ, et al. PLoS One, 2013. PMID 24349381 Free PMC Article Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. Matusiak D, et al. Am J Physiol Gastrointest Liver Physiol, 2005 Apr. PMID 15528253 Solution structure of neuromedin B by (1)H nuclear magnetic resonance spectroscopy. Lee S, et al. FEBS Lett, 1999 Oct 29. PMID 10544247

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NMBR Polyclonal Antibody, 100μg, (ATB-T3148)
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