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Na+/K+-ATPase α1 Polyclonal Antibody, 100μg, (ATB-T2973)

$199.00
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Product Details

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]Product datasheet: Overview Product Description Na+/K+-ATPase α1 Polyclonal Antibody, 100μg, (ATB-T2973) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Na+/K+-ATPase α1 around the non-phosphorylation site of S16. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Helicobacter pylori-induced posttranscriptional regulation of H-K-ATPase α-subunit gene expression by miRNA. Zhang YM, et al. Am J Physiol Gastrointest Liver Physiol, 2014 Apr 1. PMID 24503769 Does Na,K-ATPase play a role in the regulation of neurotransmitter release by prejunctional alpha-adrenoceptors? Powis DA. Biochem Pharmacol, 1981 Sep 1. PMID 21043236 [Effect of Na(+)/K(+)-ATPase alpha1 siRNA and ouabain upon cell cycle in human hepatoma HepG2 cell and its mechanism]. Xu ZW, et al. Zhonghua Yi Xue Za Zhi, 2010 Mar 30. PMID 20450619 Increased activities of Na+/K+-ATPase and Ca2+/Mg2+-ATPase in the frontal cortex and cerebellum of autistic individuals. Ji L, et al. Life Sci, 2009 Dec 16. PMID 19863947 Free PMC Article Pump and channel K (Rb+) fluxes in apoptosis of human lymphoid cell line U937. Vereninov AA, et al. Cell Physiol Biochem, 2008. PMID 18769045

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Na+/K+-ATPase α1 Polyclonal Antibody, 100μg, (ATB-T2973)
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