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Neu Polyclonal Antibody, 100μg, (ATB-T3051)
Background: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Neu Polyclonal Antibody, 100μg, (ATB-T3051) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Neu around the non-phosphorylation site of Y1248. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: [DNA structural features on the borders of ERBB2 amplicons in breast cancer]. Matsenko NIu, et al. Mol Biol (Mosk), 2013 Sep-Oct. PMID 25509354 Immunohistochemical HER2 expression not associated with clinicopathological characteristics of stage I-III gastric cancer patients. Chen XZ, et al. Hepatogastroenterology, 2014 Sep. PMID 25436385 HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer. Lee HJ, et al. Am J Clin Pathol, 2014 Dec. PMID 25389328 Increased likelihood of mastectomy in human epidermal growth factor receptor 2-positive ductal carcinoma in situ. Weiss A, et al. Am Surg, 2014 Oct. PMID 25264633 Effect of p95HER2/611CTF on the response to trastuzumab and chemotherapy. Parra-Palau JL, et al. J Natl Cancer Inst, 2014 Nov. PMID 25253614
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Why is IntelixBio LLC so popular?
IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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