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Neuropilin Polyclonal Antibody, 100μg, (ATB-T15452)

$199.00
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Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]Product datasheet: Overview Product Description Neuropilin Polyclonal Antibody, 100μg, (ATB-T15452) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Neuropilin. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Immunohistological insight into the correlation between neuropilin-1 and epithelial-mesenchymal transition markers in epithelial ovarian cancer. Adham SA, et al. J Histochem Cytochem, 2014 Sep. PMID 24850663 Investigation of a novel biomarker, neuropilin-1, and its application for poor prognosis in acute myeloid leukemia patients. Zhao J, et al. Tumour Biol, 2014 Jul. PMID 24737589 High neuropilin 1 expression was associated with angiogenesis and poor overall survival in resected pancreatic ductal adenocarcinoma. Ben Q, et al. Pancreas, 2014 Jul. PMID 24632553 NRP-1 expression in bladder cancer and its implications for tumor progression. Cheng W, et al. Tumour Biol, 2014 Jun. PMID 24627131 Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability. Plein A, et al. Microcirculation, 2014 May. PMID 24521511 Free PMC Article

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Neuropilin Polyclonal Antibody, 100μg, (ATB-T15452)
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