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Ob-R Polyclonal Antibody, 100μg, (ATB-T3226)
Background: The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]Product datasheet: Overview Product Description Ob-R Polyclonal Antibody, 100μg, (ATB-T3226) Image Species Reactivities Human,Mouse,Monkey Immunogen Synthesized peptide derived from human Ob-R around the non-phosphorylation site of Y1141. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Lack of association between LEPR Q223R polymorphisms and cancer susceptibility: evidence from a meta-analysis. Liu P, et al. J BUON, 2014 Jul-Sep. PMID 25261679 Association of LEPR K109R polymorphisms with cancer risk: a systematic review and pooled analysis. Shi H, et al. J BUON, 2014 Jul-Sep. PMID 25261678 Association of Gln223 Arg polymorphism of the leptin receptor gene with indicators of energy expenditure in obese children. Répásy J, et al. Nutrition, 2014 Jul-Aug. PMID 24985001 Low expression level of OB-Rb results from constitutive translocational attenuation attributable to a less efficient signal sequence. Choi I, et al. FEBS Lett, 2014 Jun 27. PMID 24859083 The Q223R polymorphism in the leptin receptor associates with objectively measured light physical activity in free-living Japanese. Murakami H, et al. Physiol Behav, 2014 Apr 22. PMID 24631298
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Why is IntelixBio LLC so popular?
IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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What products do you offer?
At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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We ship our medical lab equipment to customers nationwide. Browse our online shop to view our impressive inventory of available lab equipment today and purchase the products that meet your unique style and needs. We can't wait to prove why Intelixbio.com is one of the nation's best medical lab supply providers.
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When you contact our team, you can expect fast, friendly, and professional assistance with all your medical lab equipment needs.