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PC-PLD2 Polyclonal Antibody, 100μg, (ATB-T3620)

$199.00
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Product Details

Background: The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]Product datasheet: Overview Product Description PC-PLD2 Polyclonal Antibody, 100μg, (ATB-T3620) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human PC-PLD2 around the non-phosphorylation site of Y169. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells. Hwang WC, et al. Exp Mol Med, 2014 Dec 5. PMID 25475140 Free PMC Article Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition. Oguin TH 3rd, et al. J Biol Chem, 2014 Sep 12. PMID 25065577 Phospholipase D2 downregulation induces cellular senescence through a reactive oxygen species-p53-p21Cip1/WAF1 pathway. Lee YH, et al. FEBS Lett, 2014 Aug 25. PMID 25064843 Phospholipase D in cell signaling: from a myriad of cell functions to cancer growth and metastasis. Gomez-Cambronero J. J Biol Chem, 2014 Aug 15. PMID 24990944 Phospholipase D (PLD) drives cell invasion, tumor growth and metastasis in a human breast cancer xenograph model. Henkels KM, et al. Oncogene, 2013 Dec 5. PMID 23752189 Free PMC Article

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PC-PLD2 Polyclonal Antibody, 100μg, (ATB-T3620)
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