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PDLIM5 Polyclonal Antibody, 100μg, (ATB-T3647)

$199.00
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Background: This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]Product datasheet: Overview Product Description PDLIM5 Polyclonal Antibody, 100μg, (ATB-T3647) Image Species Reactivities Human Immunogen Synthesized peptide derived from human PDLIM5 around the non-phosphorylation site of Y251. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Nonsynonymous polymorphisms of the PDLIM5 gene association with the occurrence of both bipolar disorder and schizophrenia. Zain MA, et al. Psychiatr Genet, 2013 Dec. PMID 24064681 Peripheral PDLIM5 expression in bipolar disorder and the effect of olanzapine administration. Zain MA, et al. BMC Med Genet, 2012 Oct 2. PMID 23031404 Free PMC Article LIM domains regulate protein kinase C activity: a novel molecular function. Maturana AD, et al. Cell Signal, 2011 May. PMID 21266195 PDLIM5 is not a neuronal CaV2.2 adaptor protein. Gardezi SR, et al. Nat Neurosci, 2009 Aug. PMID 19636345 Positive association between the PDLIM5 gene and bipolar disorder in the Chinese Han population. Zhao T, et al. J Psychiatry Neurosci, 2009 May. PMID 19448850 Free PMC Article

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PDLIM5 Polyclonal Antibody, 100μg, (ATB-T3647)
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