Phospho-Ribosomal Protein S6 (S235) Polyclonal Antibody, 100 µg, (ATB-P0243)

Background: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.Product datasheet: Overview Product Description Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human Ribosomal Protein S6 around the phosphorylation site of S235. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year Clonality Polyclonal References: Isolation and characterization of cloned cDNAs that code for human ribosomal protein S6. Lott J.B., Mackie G.A.Gene 65:31-39(1988) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. The primary structure of the human ribosomal protein S6 derived from a cloned cDNA. Heinze H., Arnold H.H., Fischer D., Kruppa J.J. Biol. Chem. 263:4139-4144(1988) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. The organization of the intron-containing human S6 ribosomal protein (rpS6) gene and determination of its location at chromosome 9p21. Antoine M., Fried M.Hum. Mol. Genet. 1:565-570(1992) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. The human ribosomal protein S6 gene: isolation, primary structure and location in chromosome 9. Pata I., Hoth S., Kruppa J., Metspalu A.Gene 121:387-392(1992) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Identification of immuno-peptidmics that are recognized by tumor-reactive CTL generated from TIL of colon cancer patients. Shichijo S., Itoh K.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Colon adenocarcinoma. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-221. Tissue: Colon, Muscle, Pancreas, Skin and Testis. Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. Vladimirov S.N., Ivanov A.V., Karpova G.G., Musolyamov A.K., Egorov T.A., Thiede B., Wittmann-Liebold B., Otto A.Eur. J. Biochem. 239:144-149(1996) [PubMed] [Europe PMC] Cited for: PROTEIN SEQUENCE OF 1-15. Tissue: Placenta. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.Cell 127:635-648(2006) [PubMed] [Europe PMC] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. Roux P.P., Shahbazian D., Vu H., Holz M.K., Cohen M.S., Taunton J., Sonenberg N., Blenis J.J. Biol. Chem. 282:14056-14064(2007) [PubMed] [Europe PMC] Cited for: PHOSPHORYLATION AT SER-235 AND SER-236. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. Tissue: Cervix carcinoma.