Protocadherin-11 Polyclonal Antibody, 100µg, (ATB-T3863)

Background: Potential calcium-dependent cell-adhesion protein.Product datasheet: Overview Product Description Protocadherin-11 Polyclonal Antibody, 100µg, (ATB-T3863) Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human Protocadherin-11. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year Clonality Polyclonal References: Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain. Blanco P., Sargent C.A., Boucher C., Mitchell M., Affara N.Mamm. Genome 11:906-914(2000) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), TISSUE SPECIFICITY. Tissue: Brain. The emergence of protocadherin-PC expression during the acquisition of apoptosis-resistance by prostate cancer cells. Chen M.-W., Vacherot F., De La Taille A., Gil-Diez-De-Medina S., Shen R., Friedman R.A., Burchardt M., Chopin D.K., Buttyan R.Oncogene 21:7861-7871(2002) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), INTERACTION WITH CTNNB1, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Prostatic carcinoma. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. , Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C.Nature 423:825-837(2003) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), VARIANTS PHE-917 AND LYS-1012. Tissue: Brain. Protocadherin X (PCDHX) and Y (PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains. Blanco-Arias P., Sargent C.A., Affara N.A.Mamm. Genome 15:41-52(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1109 AND 1119-1340, NUCLEOTIDE SEQUENCE [MRNA] OF 213-1340 (ISOFORM 4), TISSUE SPECIFICITY, ALTERNATIVE SPLICING. Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. Lu W., van Eerde A.M., Fan X., Quintero-Rivera F., Kulkarni S., Ferguson H., Kim H.-G., Fan Y., Xi Q., Li Q.-G., Sanlaville D., Andrews W., Sundaresan V., Bi W., Yan J., Giltay J.C., Wijmenga C., de Jong T.P.V.M. , Feather S.A., Woolf A.S., Rao Y., Lupski J.R., Eccles M.R., Quade B.J., Gusella J.F., Morton C.C., Maas R.L.Am. J. Hum. Genet. 80:616-632(2007) [PubMed] [Europe PMC] Cited for: CHROMOSOMAL TRANSLOCATION WITH ROBO2. Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders. Durand C.M., Kappeler C., Betancur C., Delorme R., Quach H., Goubran-Botros H., Melke J., Nygren G., Chabane N., Bellivier F., Szoke A., Schurhoff F., Rastam M., Anckarsaeter H., Gillberg C., Leboyer M., Bourgeron T.Am. J. Med. Genet. B Neuropsychiatr. Genet. 141:67-70(2006) [PubMed] [Europe PMC] Cited for: VARIANTS PHE-917 AND LYS-1012, TISSUE SPECIFICITY.