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RDM1 Polyclonal Antibody, 100μg, (ATB-T4034)

$199.00
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Product Details

Background: This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description RDM1 Polyclonal Antibody, 100μg, (ATB-T4034) Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human RDM1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress. Messaoudi L, et al. Nucleic Acids Res, 2007. PMID 17905820 Free PMC Article RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates. Hamimes S, et al. J Biol Chem, 2005 Mar 11. PMID 15611051 WRN interacts physically and functionally with the recombination mediator protein RAD52. Baynton K, et al. J Biol Chem, 2003 Sep 19. PMID 12750383 Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348 A proteome-scale map of the human interactome network. Rolland T, et al. Cell, 2014 Nov 20. PMID 25416956

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RDM1 Polyclonal Antibody, 100μg, (ATB-T4034)
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