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RECK Polyclonal Antibody, 100μg, (ATB-T4036)

$199.00
In stock
Product Details

Background: The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description RECK Polyclonal Antibody, 100μg, (ATB-T4036) Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the N-terminal region of human RECK. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Clinical significance of RECK promoter methylation in pancreatic ductal adenocarcinoma. Lu XX, et al. Tumour Biol, 2013 Dec. PMID 23749490 Effect of RECK gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic features. Chung TT, et al. PLoS One, 2012. PMID 22428065 Free PMC Article The silencing of RECK gene is associated with promoter hypermethylation and poor survival in hepatocellular carcinoma. Zhang C, et al. Int J Biol Sci, 2012. PMID 22419890 Free PMC Article Low expression of RECK indicates a shorter survival for patients with invasive breast cancer. Zhang Y, et al. Cancer Sci, 2012 Jun. PMID 22404079 Reversion-inducing cysteine-rich protein with Kazal motif (RECK) expression: an independent prognostic marker of survival in colorectal cancer. Stenzinger A, et al. Hum Pathol, 2012 Aug. PMID 22397871

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RECK Polyclonal Antibody, 100μg, (ATB-T4036)
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