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RGS14 Polyclonal Antibody, 100μg, (ATB-T4073)
Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description RGS14 Polyclonal Antibody, 100μg, (ATB-T4073) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human RGS14. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins. Zhao P, et al. J Cell Biochem, 2013 Jun. PMID 23255434 Free PMC Article Backbone and sidechain 1H, 13C and 15N resonance assignments of the RGS domain from human RGS14. Dowler EF, et al. Biomol NMR Assign, 2007 Jul. PMID 19636837 RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways. Cho H, et al. Mol Pharmacol, 2000 Sep. PMID 10953050 Regulator of G-protein signaling 14 protein modulates Ca²+ influx through Cav1 channels. Martín-Montañez E, et al. Neuroreport, 2010 Nov 17. PMID 20842066 Free PMC Article RGS14 is a microtubule-associated protein. Martin-McCaffrey L, et al. Cell Cycle, 2005 Jul. PMID 15917656
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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