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Rab 11B Polyclonal Antibody, 100μg, (ATB-T3919)

$199.00
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Product Details

Background: The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]Product datasheet: Overview Product Description Rab 11B Polyclonal Antibody, 100μg, (ATB-T3919) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human Rab 11B. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling. Haugsten EM, et al. Traffic, 2014 Jun. PMID 24589086 Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B. Agop-Nersesian C, et al. PLoS Pathog, 2010 Jul 29. PMID 20686666 Free PMC Article The crystal structure of the small GTPase Rab11b reveals critical differences relative to the Rab11a isoform. Scapin SM, et al. J Struct Biol, 2006 Jun. PMID 16545962 Crystal structure of the cGMP-dependent protein kinase II leucine zipper and Rab11b protein complex reveals molecular details of G-kinase-specific interactions. Reger AS, et al. J Biol Chem, 2014 Sep 12. PMID 25070890 Rab11b mediates melanin transfer between donor melanocytes and acceptor keratinocytes via coupled exo/endocytosis. Tarafder AK, et al. J Invest Dermatol, 2014 Apr. PMID 24141907

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Rab 11B Polyclonal Antibody, 100μg, (ATB-T3919)
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