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Rab 1B Polyclonal Antibody, 100μg, (ATB-T3921)

$199.00
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Background: Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]Product datasheet: Overview Product Description Rab 1B Polyclonal Antibody, 100μg, (ATB-T3921) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Rab 1B. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Rab1b overexpression modifies Golgi size and gene expression in HeLa cells and modulates the thyrotrophin response in thyroid cells in culture. Romero N, et al. Mol Biol Cell, 2013 Mar. PMID 23325787 Free PMC Article Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. Mihai Gazdag E, et al. EMBO Rep, 2013 Feb. PMID 23288104 Free PMC Article Role of Rab1b in COPII dynamics and function. Slavin I, et al. Eur J Cell Biol, 2011 Apr. PMID 21093099 Autophagosome formation depends on the small GTPase Rab1 and functional ER exit sites. Zoppino FC, et al. Traffic, 2010 Sep. PMID 20545908 A bifunctional bacterial protein links GDI displacement to Rab1 activation. Machner MP, et al. Science, 2007 Nov 9. PMID 17947549

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Rab 1B Polyclonal Antibody, 100μg, (ATB-T3921)
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