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Rabr Polyclonal Antibody, 100μg, (ATB-T3951)

$199.00
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Product Details

Background: This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013]Product datasheet: Overview Product Description Rabr Polyclonal Antibody, 100μg, (ATB-T3951) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the Internal region of human Rabr. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport. Doria M, et al. J Cell Biol, 1999 Dec 27. PMID 10613896 Free PMC Article A protein-binding domain, EH, identified in the receptor tyrosine kinase substrate Eps15 and conserved in evolution. Wong WT, et al. Proc Natl Acad Sci U S A, 1995 Oct 10. PMID 7568168 Free PMC Article Rev-ing up post-transcriptional HIV-1 RNA expression. Yedavalli VS, et al. RNA Biol, 2011 Mar-Apr. PMID 21358275 Free PMC Article Cellular proteins and HIV-1 Rev function. Suhasini M, et al. Curr HIV Res, 2009 Jan. PMID 19149558 Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. Glöckner G, et al. Genome Res, 1998 Oct. PMID 9799793 Free PMC Article

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Rabr Polyclonal Antibody, 100μg, (ATB-T3951)
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