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Rev-erbα Polyclonal Antibody, 100μg, (ATB-T4058)

$199.00
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Product Details

Background: This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]Product datasheet: Overview Product Description Rev-erbα Polyclonal Antibody, 100μg, (ATB-T4058) Image Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human Rev-erbα. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: RevErbα preferentially deforms DNA by induced fit. Chung YH, et al. Chembiochem, 2014 Mar 21. PMID 24677802 The thyroid hormone receptor alpha locus and white matter lesions: a role for the clock gene REV-ERBα. Medici M, et al. Thyroid, 2012 Nov. PMID 23083441 Free PMC Article Rev-erb-alpha: an integrator of circadian rhythms and metabolism. Duez H, et al. J Appl Physiol (1985), 2009 Dec. PMID 19696364 Free PMC Article Association study in a Sardinian sample between bipolar disorder and the nuclear receptor REV-ERBalpha gene, a critical component of the circadian clock system. Severino G, et al. Bipolar Disord, 2009 Mar. PMID 19267705 Association analysis of nuclear receptor Rev-erb alpha gene (NR1D1) with mood disorders in the Japanese population. Kishi T, et al. Neurosci Res, 2008 Dec. PMID 18804497

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Rev-erbα Polyclonal Antibody, 100μg, (ATB-T4058)
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