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Ribosomal Protein L11 Polyclonal Antibody, 100μg, (ATB-T4094)

$199.00
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Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Dec 2010]Product datasheet: Overview Product Description Ribosomal Protein L11 Polyclonal Antibody, 100μg, (ATB-T4094) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human Ribosomal Protein L11. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation. Bhat KP, et al. EMBO J, 2004 Jun 16. PMID 15152193 Free PMC Article [Structural and functional analysis of the human ribosomal protein L11 gene]. Voronina EN, et al. Mol Biol (Mosk), 2003 May-Jun. PMID 12815950 Assignment of the L11 ribosomal protein gene (RPL11) to human chromosome 1p36.1-->p35 by in situ hybridization. Graphodatsky AS, et al. Cytogenet Cell Genet, 1999. PMID 10343117 [Cloning and determination of the primary structure of DNA complementary to the mRNA of human ribosomal protein L11]. Mishin VP, et al. Bioorg Khim, 1995 Feb. PMID 7748210 Loss of tumor suppressor RPL5/RPL11 does not induce cell cycle arrest but impedes proliferation due to reduced ribosome content and translation capacity. Teng T, et al. Mol Cell Biol, 2013 Dec. PMID 24061479 Free PMC Article

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Ribosomal Protein L11 Polyclonal Antibody, 100μg, (ATB-T4094)
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