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Ribosomal Protein S15 Polyclonal Antibody, 100μg, (ATB-T4124)
Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19P family of ribosomal proteins. It is located in the cytoplasm. This gene has been found to be activated in various tumors, such as insulinomas, esophageal cancers, and colon cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Ribosomal Protein S15 Polyclonal Antibody, 100μg, (ATB-T4124) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human Ribosomal Protein S15. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Nuclear export and cytoplasmic processing of precursors to the 40S ribosomal subunits in mammalian cells. Rouquette J, et al. EMBO J, 2005 Aug 17. PMID 16037817 Free PMC Article Isolation and characterization of the human homologue of rig and its pseudogenes: the functional gene has features characteristic of housekeeping genes. Shiga K, et al. Proc Natl Acad Sci U S A, 1990 May. PMID 2159154 Free PMC Article Evolutionary conservation of the insulinoma gene rig and its possible function. Inoue C, et al. Proc Natl Acad Sci U S A, 1987 Oct. PMID 2821540 Free PMC Article rig encodes ribosomal protein S15. The primary structure of mammalian ribosomal protein S15. Kitagawa M, et al. FEBS Lett, 1991 Jun 3. PMID 2044758 Ribosomal proteins RPL37, RPS15 and RPS20 regulate the Mdm2-p53-MdmX network. Daftuar L, et al. PLoS One, 2013. PMID 23874713 Free PMC Article
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