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Rsu-1 Polyclonal Antibody, 100μg, (ATB-T4186)

$199.00
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Background: This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description Rsu-1 Polyclonal Antibody, 100μg, (ATB-T4186) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the Internal region of human Rsu-1. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Identification of an alternatively spliced RNA for the Ras suppressor RSU-1 in human gliomas. Chunduru S, et al. J Neurooncol, 2002 Dec. PMID 12510772 The Ras suppressor RSU-1 localizes to 10p13 and its expression in the U251 glioblastoma cell line correlates with a decrease in growth rate and tumorigenic potential. Tsuda T, et al. Oncogene, 1995 Jul 20. PMID 7624154 CUBN is a gene locus for albuminuria. Böger CA, et al. J Am Soc Nephrol, 2011 Mar. PMID 21355061 Free PMC Article The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells. Dougherty GW, et al. Eur J Cell Biol, 2008 Sep. PMID 18436335 Free PMC Article Increased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activation. Masuelli L, et al. Mol Cell Biol, 1996 Oct. PMID 8816460 Free PMC Article

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Rsu-1 Polyclonal Antibody, 100μg, (ATB-T4186)
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