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SETMAR Polyclonal Antibody, 100μg, (ATB-T4260)
Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]Product datasheet: Overview Product Description SETMAR Polyclonal Antibody, 100μg, (ATB-T4260) Species Reactivities Human Immunogen Synthesized peptide derived from the Internal region of human SETMAR. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing. Rath A, et al. BMC Mol Biol, 2014 Mar 22. PMID 24655462 Free PMC Article Delineation of known and new transcript variants of the SETMAR (Metnase) gene and the expression profile in hematologic neoplasms. Jeyaratnam DC, et al. Exp Hematol, 2014 Jun. PMID 24607956 The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart. Kim HS, et al. J Biol Chem, 2014 Apr 11. PMID 24573677 Free PMC Article Biochemical characterization of metnase's endonuclease activity and its role in NHEJ repair. Beck BD, et al. Biochemistry, 2011 May 24. PMID 21491884 Free PMC Article Crystal structure of the human Hsmar1-derived transposase domain in the DNA repair enzyme Metnase. Goodwin KD, et al. Biochemistry, 2010 Jul 13. PMID 20521842
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IntelixBio has swiftly become a household name in the medical industry, primarily owing to its cutting-edge medical lab equipment. Our commitment to excellence resonates through every facet of our products, ensuring that laboratories worldwide receive top-tier solutions for their diagnostic needs. Our medical lab equipment is engineered with precision and innovation, embodying the pinnacle of technological advancement in the field. From state-of-the-art analyzers to automated specimen-handling systems, our extensive catalog caters to diverse laboratory requirements, fostering efficiency and accuracy in every diagnostic process. Laboratories entrust IntelixBio's medical lab equipment for its unwavering reliability, empowering healthcare professionals with the tools they need to deliver optimal patient care.
At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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At IntelixBio LLC, we offer high-quality medical lab equipment. Our lab supplies include:
- Protective gear
- Antibody immunodetection supplies
- Bioreagents
- Lab Supplies
- Immunohistochemistry Tools
- Instruments and Equipment
- PPE
- Sample preparation supplies
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