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SFRS11 Polyclonal Antibody, 100μg, (ATB-T4263)

$199.00
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Background: This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010]Product datasheet: Overview Product Description SFRS11 Polyclonal Antibody, 100μg, (ATB-T4263) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the Internal region of human SFRS11. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54(nrb), an event linked to G2/M arrest. Casado P, et al. J Proteomics, 2009 Jan 30. PMID 18832053 Primary structure of a human arginine-rich nuclear protein that colocalizes with spliceosome components. Chaudhary N, et al. Proc Natl Acad Sci U S A, 1991 Sep 15. PMID 1896467 Free PMC Article SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy. Wu JY, et al. Mol Cell Biol, 2006 Sep. PMID 16943417 Free PMC Article PUF60: a novel U2AF65-related splicing activity. Page-McCaw PS, et al. RNA, 1999 Dec. PMID 10606266 Free PMC Article The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction. Straub T, et al. J Biol Chem, 1998 Oct 9. PMID 9756848

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SFRS11 Polyclonal Antibody, 100μg, (ATB-T4263)
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